Cannabis and Borneol
Browse the latest research linking medical marijuana / medicinal cannabis and Borneol.
(terpene) Borneol is a bicyclic organic compound and a terpene derivative.
Click on a study title below to open a new tab with full article, or click on a compound to see it's full list of research.
Compounds Topics Title Date
Borneol anti-inflamatory,pain in mice via placebo trial (n=36) Borneol, a Bicyclic Monoterpene Alcohol, Reduces Nociceptive Behavior and Inflammatory Response in Mice Apr 2013
Ingestion Method: 5, 25, and 50 mg/kg
Together, our results suggest that borneol possess significant central and peripheral antinociceptive activity; it has also anti-inflammatory activity. In addition, borneol did not impair motor coordination.
Borneol pain in vitro Inhibition of acetylcholine-mediated effects by borneol. Jan 2003
The inhibitory effect by borneol is more potent than the effect by lidocaine, a commonly used local anesthetic. The data suggest that borneol specifically inhibits the nAChR-mediated effects in a noncompetitive way.
Borneol drug potentiator in mice Effect of borneol on the distribution of gastrodin to the brain in mice via oral administration. Feb 2008
Compared with the administration of gastrodin alone, gastrodin coadministrated with borneol could have been rapidly absorbed from the gastrointestinal tract; the peak time of gastrodin in the plasma became shorter (5-15 vs. 30 min); the bioavailability of gastrodigenin in the brain was increased by 33.6-108.8%; and obvious brain-targeting effect was observed.
Borneol anti-coagulant in vitro The antithrombotic effect of borneol related to its anticoagulant property. 2008
It suggested that the antithrombotic activity of borneol and its action in combined formula for preventing cardiovascular diseases might be due to anticoagulant activity rather than antiplatelet activity.
Borneol anti-fibrosis in mice via model Influence of borneol on primary mice oral fibroblasts: a penetration enhancer may be used in oral submucous fibrosis. Mar 2009
Ingestion Method: 18.75 to 300 microg/ml
This study indicates that borneol has anti-fibrosis activity and the mechanism may partly be relevant to its inhibiting effects on fibroblasts mitosis, collagen and TIMP-1 production. It can be safely used as a penetration enhancer for our formula to treat OSF.
Borneol anti-oxidant in vitro Borneol alleviates oxidative stress via upregulation of Nrf2 and Bcl-2 in SH-SY5Y cells Dec 2011
Borneol protected SH-SY5Y cells against Abeta--induced toxicity, exerted an antioxidative effect and suppressed apoptosis. It increases our knowledge about neuroprotective mechanism of borneol, and it is hopeful to be a candidate compound for developing therapeutic drug for the prevention and treatment of AD and other Abeta--related neurodegenerative diseases.
Borneol anti-inflamatory in vitro Identification of 1,8-cineole, borneol, camphor, and thujone as anti-inflammatory compounds in a Salvia officinalis L. infusion using human gingival fibroblasts. Mar 2013
Ingestion Method: Salvia officinalis L. infusion
Therefore, the volatile compounds were found to be more effective than rosmarinic acid. 1,8-Cineole, borneol, camphor, and alpha--/beta--thujone chiefly contribute to the anti-inflammatory activity of sage infusion in human gingival fibroblasts.
Borneol drug potentiator in rats Improved blood-brain barrier distribution: Effect of borneol on the brain pharmacokinetics of kaempferol in rats by in vivomicrodialysis sampling Mar 2015
Borneol can enhance the blood brain barrier permeability and improve the transportation of Kaempferol to brain.
Borneol anti-oxidant in vitro A new source of natural D-borneol and its characteristic Nov 2010
Ingestion Method: The essential oils from leaves of Mei Pian tree
Antioxidant activities of the refined D-borneol and standard D-borneol were determined by testing their DPPH and hydroxyl radicals scavenging activities and the reducing power. The refined D-borneol and standard D-borneol had the same antioxidant activity.