|Guaiol||laxative via review||Pubchem - Guaiol||Jan 2019|
|Used by herbalists as a laxative; diuretic.|
|Guaiol||cancer,lung cancer in mice via experiment||(-)-Guaiol regulates RAD51 stability via autophagy to induce cell apoptosis in non-small cell lung cancer||Sept 2016|
Action Pathway: RAD51|
The following mechanism studies show that (-)-Guaiol is involved in cell autophagy to regulate the expression of RAD51, leading to double-strand breaks triggered cell apoptosis.
|Guaiol||anti-bacterial,anti-oxidant||The essential oil from the fruits of the Brazilian spice Xylopia sericea A. St.-Hil. presents expressive in-vitro anti-bacterial and anti-oxidant activity.||Mar 2017|
Ingestion Method: Xylopia sericea fruits (OXS)|
OXS presented a significant antioxidant activity and also a high bacteriostatic effect against Staphylococcus aureus, Enterobacter cloacae, Bacillus cereus and Klebsiella pneumoniae.
|Guaiol,Caryophyllene||cancer,lung cancer in vitro via experiment||Bulnesia sarmientoi Supercritical Fluid Extract Exhibits Necroptotic Effects and Anti-Metastatic Activity on Lung Cancer Cells.||Dec 2018|
|alpha--Guaiene, (-)-guaiol and beta--caryophyllene are responsible for most of the cytotoxic activity of BSE against these two cancer cell lines. Since BSE possesses significant cytotoxicity and anti-metastatic activity on A549 and H661 cells, it may serve as a potential target for the treatment of lung cancer.|