Cannabis and Myrcene
Browse the latest research linking medical marijuana / medicinal cannabis and Beta-Myrcene (Myrcene).
(terpene) Most commonly found terpene in cannabis. [Wikipedia]
Click on a study title below to open a new tab with full article, or click on a compound to see it's full list of research.
Compounds Topics Title Date
Myrcene cancer,breast cancer in vitro via experiment Anti-invasive effect of Beta-myrcene, a component of the essential oil from Pinus koraiensis cones, in metastatic MDA-MB-231 human breast cancer cells Aug 2015
Pretreatment with beta--myrcene suppressed TNFalpha--induced phosphorylation of inhibitor of kappa-B kinase and NF-kappa-B as well as matrix metalloproteinase-9 (MMP-9) gene expression in a dose-dependent fashion. Furthermore, beta--myrcene inhibited TNFalpha--induced invasion of MDA-MB-231 cells as determined by three-dimensional spheroid invasion assays.
Myrcene,Caryophyllene anxiety in humans via experiment (n=5) Cannabis Essential Oil: A Preliminary Study for the Evaluation of the Brain Effects. Jan 2018
These results suggest that the brain wave activity and ANS are affected by the inhalation of the EO of Cannabis sativasuggesting a neuromodular activity in cases of stress, depression, and anxiety.
THC,cannabis,Myrcene,Caryophyllene pain,headache in humans via survey (n=2032) Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis cohort May 2018
Positive  Hybrid strains were preferred in ID Migraine(TM), headache, and most pain groups, with OG Shark, a high THC (delta-9-tetrahydrocannabinol)/THCA (tetrahydrocannabinolic acid), low CBD (cannabidiol)/CBDA (cannabidiolic acid), strain with predominant terpenes beta--caryophyllene and beta--myrcene, most preferred in the headache and ID Migraine(TM) groups
Myrcene anxiety,sedative in mice via experiment Central effects of citral, myrcene and limonene, constituents of essential oil chemotypes from Lippia alba (Mill.) N.E. Brown Nov 2004
Ingestion Method: 100 and 200 mg/kg
Our study showed that citral, limonene and myrcene presented sedative as well as motor relaxant effects.
Myrcene,Limonene anti-inflamatory in mice Evaluation of anti-inflammatory activity of essential oils from two Asteraceae species. Aug 2003
The oils, when administered orally, were able to inhibit the LPS-induced inflammation including cell migration; with a similar effect being observed for pure limonene.
Myrcene pain in rats Myrcene mimics the peripheral analgesic activity of lemongrass tea Aug 1991
Oral administration of an infusion of lemongrass (Cymbopogon citratus) fresh leaves to rats produced a dose-dependent analgesia for the hyperalgesia induced by subplantar injections of either carrageenin or prostaglandin E2, but did not affect that induced by dibutyryl cyclic AMP
Myrcene,Linalool,Eucalyptol anti-oxidant in vitro Protective effect of linalool, myrcene and eucalyptol against t-butyl hydroperoxide induced genotoxicity in bacteria and cultured human cells Jan 2009
Ingestion Method: 0.05-1.5 mg/plate and 0.01-1.0 microg/ml
The results indicate that linalool, eucalyptol and myrcene have substantial protective effect against oxidant induced genotoxicity, which is predominately mediated by their radical scavenging activity.
Myrcene pain in mice via experiment Effect of myrcene on nociception in mice. Dec 1990
Ingestion Method: 10 and 20 mg kg-1 (i.p.) or at 20 and 40 mg kg-1 (s.c.)
The results suggest that myrcene is capable of inducing antinociception in mice, probably mediated by alpha 2-adrenoceptor stimulated release of endogenous opioids.
Myrcene anti-oxidant in mice via experiment (n=40) Neuroprotective effects of Beta-myrcene following global cerebral ischemia/reperfusion-mediated oxidative and neuronal damage in a C57BL/J6 mouse June 2014
Ingestion Method: 200 mg/kg
However, MYR treatment protected against the oxidative effects of I/R by inducing significant increases in GSH, GPx, and SOD and a significant decrease in the formation of TBARS. Additionally, cerebral I/R increased the incidence of histopathological damage and apoptosis in brain tissue, but these neurodegenerative effects were eliminated by MYR treatment.
Caryophyllene,Myrcene arthritis,anti-inflamatory in vitro Evaluation of the anti-inflammatory, anti-catabolic and pro-anabolic effects of E-caryophyllene, myrcene and limonene in a cell model of osteoarthritis Mar 2015
These data show that myrcene has significant anti-inflammatory and anti-catabolic effects in human chondrocytes and, thus, its ability to halt or, at least, slow down cartilage destruction and osteoarthritis progression warrants further investigation.
Myrcene anti-bacterial in vitro via experiment The anti-bacterial Effects of Myrcene on Staphylococcus aureus and Its Role in the Essential Oil of the Tea Tree (Melaleuca alternifolia) Feb 2004
Myrcene acts as an antibacterial agent against S. aureus and is an important contributor to the antibacterial activity of TTO.