| 2AG,ANA |
sexual health
in rats via experiment |
Endocannabinoids Interact With the Dopaminergic System to Increase Sexual Motivation: Lessons From the Sexual Satiety Phenomenon |
Aug 2019 |
|
Based on these data, it could be thought that sexual motivation is diminished during the long-lasting sexual inhibitory period that characterizes sexually exhausted rats and that eCBs reverse that inhibition through the modulation of the dopaminergic system.
|
| ANA |
cancer,breast cancer
in vitro |
The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation |
Jun 1998 |
|
These data suggest that anandamide blocks human breast cancer cell proliferation through CB1-like receptor-mediated inhibition of endogenous prolactin action at the level of prolactin receptor.
|
| ANA |
autism
via review |
Endocannabinoid signaling in the control of social behavior |
May 2017 |
|
Based on translational evidence, these actions of anandamide are postulated to be important in social impairment related to (i) schizophrenia, in which tempering social anxiety might be dysfunctional, as well as in (ii) ASD, where a primary deficit may be in nucleus accumbens-regulated social reward.
|
| ANA |
cancer,prostate cancer
in vitro |
Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: implication of epidermal growth factor receptor down-regulation and ceramide production. |
Jun 2003 |
|
The potent anti-proliferative and cytotoxic effects of ANA on metastatic prostatic cancer cells might provide basis for the design of new therapeutic agents for effective treatment of recurrent and invasive prostatic cancers.
|
| ANA |
metabolism
via review |
Brain activity of anandamide: a rewarding bliss? |
Mar 2019 |
|
We will also discuss how modulation of anandamide levels through inhibition of enzymatic metabolic pathways could provide a basis for developing new pharmaco-therapeutic tools for the treatment of substance use disorders.
|