Browse our indexed database of cannabis-related medical studies and journal articles by Topic or Compound by using the tabs above.
The index currently contains 602 studies of 59 compounds across 128 topics.
| Topics | Class | # of Papers | Description |
|---|---|---|---|
| Acne | condition | 1 | |
| Addiction | condition | 14 | Cannabis and cannabinoids and the treatment of addiction disorders |
| Attention Deficit Hyperactive Disorder | condition | 7 | |
| Adolescent Use | topic | 11 | The effects of youth and adolescent use of cannabis and cannabinoids |
| Alzheimer's Disease | condition | 11 |
Alzheimer's disease is a type of dementia that causes problems with memory, thinking and behavior
See also: memory neuroprotective |
| Anti-bacterial | property | 11 | Slows or halts growth of bacteria |
| Anti-coagulant | property | 1 |
Prevents blood clots
See also: stroke |
| anti-convulsant | property | 4 |
See also: epilepsy |
| Anti-fibrosis | property | 2 | Inhibits growth of scar tissue |
| anti-fungal | property | 5 | |
| Anti-inflamatory | property | 52 |
Verdict: Positive with Moderate evidence level Multiple cannabinoids and terpenes have been shown to releive inflamation. See also: pain |
| anti-microbial | property | 2 | |
| anti-oxidant | property | 19 | |
| anti-psychotic | property | 4 | |
| Anti-viral | property | 7 | Destroys viruses |
| Anxiety | condition | 18 |
Verdict: Positive with Moderate evidence level Anxiety is an accepted use of medical cannabis in many jurisdictions. |
| Appetite Boost | property | 9 |
Verdict: Positive with Moderate evidence level Medical cannabis (via THC) is an accepted treatment for chemotherapy and AIDS induced appetite loss |
| Appetite Supress | property | 4 | |
| Osteoarthritis | condition | 6 |
See also: ra |
| Asthma | condition | 2 |
Verdict: Negative with Moderate evidence level |
| Autism | condition | 10 | ASD and other social disorders have been linked to imbalances of the endocannabinoid system |
| Bladder Dysfunction | condition | 1 | |
| Bladder Cancer | condition | 1 | |
| Blood Cancer | condition | 2 |
See also: cancer |
| High Blood Pressure | symptom | 1 |
See also: vasorelaxant |
| High Blood Sugar | symptom | 0 |
See also: diabetes |
| Boost Immune System | property | 1 | |
| Breast Cancer | condition | 15 | |
| Breath-hold Duration | topic | 2 |
Verdict: Negative with High evidence level Holding hits in longer does NOT result in higher or longer intoxication |
| Cancer | condition | 95 |
Verdict: Neutral with Moderate evidence level While Cannabis is an accepted treatment for several cancer side-effects, direct evidence in humans is lacking. Cannabinoid signalling implicated in vitro in the growth cycles of several tumor types. |
| Cardiovascular | topic | 4 | |
| Cervical Cancer | condition | 1 | |
| Chemotaxonomy | topic | 8 | |
| Chemotherapy | topic | 6 |
Verdict: Positive with High evidence level Medical Cannabis has been aproved for the treatment of chemotherapy side effects. See also: nausea |
| High Cholesterol | symptom | 3 | |
| Chronic Pain | symptom | 3 |
See also: pain |
| Colon | topic | 1 | |
| Colon Cancer | condition | 8 | |
| Cannabis Consumption Methods | topic | 2 | |
| Chronic Obstructive Pulmonary Disease | condition | 2 | |
| Crime | topic | 2 | Effects of cannabis legalization on crime rates |
| Crohn's Disease | condition | 2 |
See also: ibd |
| Cannabis Use Disorder | condition | 13 | |
| Cultivation | topic | 4 | |
| Depression | condition | 10 | |
| Diabetes | condition | 26 |
Verdict: Positive with Low evidence level Cannabis use appears to have a protective effect with respect to diabetes, although mechanisms are not known. |
| Duchenne muscular dystrophy | condition | 1 | |
| Driving | topic | 6 | Driving under the influence of cannabis |
| Drug Potentiator | topic | 16 | Influences or affects the metabolism of another drug |
| EB | condition | 1 | EB is blistering condition, in which even minor knocks and friction can cause the skin to blister or ulcer. |
| Elderly | topic | 2 | Considerations for the use of cannabis and cannabinoids by elderly people |
| Endocannibanoid System | topic | 1 | |
| Entourage Effect | topic | 7 | |
| Epilepsy | condition | 12 |
See also: anti-convulsant |
| Excercise | topic | 2 | Excercising under the influence of cannabis |
| Extraction | topic | 1 | Cannabis extraction processes |
| Fibromyalgia | condition | 2 | |
| Fragile X Syndrome | condition | 2 | |
| Gastroparesis | condition | 1 | |
| Gender Differences | topic | 2 | Differences of Cannabis metabolism or endocannibanoid systems of men and women |
| Glioma | condition | 8 |
See also: cancer |
| Graft vs Host Disease | condition | 4 | |
| Headache | symptom | 5 | |
| Heartburn | symptom | 0 | |
| Heroin Addiction | condition | 1 |
See also: addiction |
| Herpes Virus | condition | 1 | |
| History | topic | 1 | History of Cannabis |
| Human Immunodeficiency Virus | condition | 6 |
See also: appetite boost pain neuropathy |
| Huntingtons Disease | condition | 2 | |
| Cannabis Hyperemesis Disorder | condition | 6 | |
| Inflamatory Bowel Disease | condition | 8 |
See also: crohns |
| Insomnia | condition | 3 | |
| Intestinal Health | topic | 1 | |
| Kidney Cancer | condition | 1 |
See also: cancer |
| Laxative | property | 1 | |
| Leg Ulcuers | condition | 1 | |
| Leukemia | condition | 5 |
See also: cancer |
| Liver | topic | 16 | Fatty Liver Disease and other liver-released disorders |
| Lung cancer | condition | 10 |
See also: cancer |
| Malaria | condition | 1 | |
| Melanoma | condition | 1 |
See also: cancer |
| Memory | topic | 2 |
See also: alzheimers |
| Metabolism | topic | 12 | |
| Methamphetamine Addiction | condition | 2 |
See also: addiction |
| Migraine Headache | condition | 5 |
See also: pain headache |
| Multiple Sclerosis | condition | 8 |
Verdict: Positive with Moderate evidence level Medical cannabis has been shown superior to placebo in reducing pain and spasticity in MS patients in human placeo trials. See also: pain spasticity |
| Nausea | symptom | 7 | |
| Neuropathy | symptom | 7 |
Verdict: Positive with Moderate evidence level Neuropathic Pain |
| Neuroprotective | property | 8 |
See also: parkinsons |
| Nicotine Addiction | condition | 2 |
Use of cannabinoids for Cigarette/Tobbaco sessasion
See also: addiction |
| Obesity | condition | 9 |
See also: weight loss |
| Obsessive Compusive Disorder | condition | 1 | |
| Opioid Addiction | condition | 16 | |
| Oral cancer | condition | 2 |
See also: cancer |
| Ovarian Cancer | condition | 1 |
See also: cancer |
| Pain | symptom | 50 |
Verdict: Positive with Moderate evidence level While not an ideal first-line treatment, cannabis and syntheic cannabinoids have been shown as effective anaglesics, especially against neuropathic pain. See also: anti-inflamatory neuropathy |
| Pancreatic Cancer | condition | 4 |
See also: cancer |
| Parkinsons Disease | condition | 5 | |
| Chronic Pelvic Pain | condition | 1 | |
| Pharmacology | topic | 2 | Cannabis and Cannabinoids Pharmacology |
| Placebo Effects | topic | 1 | |
| Pregnancy | topic | 9 |
Verdict: Negative with Medium evidence level Cannabis use during pregnancy has been linked to low birth weight and increased rate of miscarriage. |
| Prostate Cancer | condition | 9 | |
| Post-Traumatic Stress Disorder | condition | 11 | |
| Rheumatoid Arthritis | condition | 4 |
See also: arthritis |
| Renal Cell Carcinoma | condition | 1 | |
| Rett Syndrome | condition | 1 | |
| Safety | topic | 14 | |
| Schitzophrenia | condition | 2 | |
| Second-Hand Smoke | topic | 5 | |
| Sedative | property | 16 | Sleeping aids |
| Sexual Health | topic | 8 | Effects of Cannabis and Cannabinoids on sexual health |
| Side Effects | topic | 2 | |
| Skin Cancer | condition | 4 |
See also: cancer |
| Sleep | symptom | 7 |
See also: sedative |
| Spasticity | symptom | 4 |
Verdict: Positive with High evidence level Cannabis is an accepted medical use for the treatment of spasticity. |
| Stomach Cancer | condition | 1 |
See also: cancer |
| Stress | symptom | 3 | |
| Stroke | condition | 3 |
See also: cardiovascular anti-coagulant |
| Traumatic Brain Injury | condition | 1 | |
| Testicular Cancer | condition | 2 | |
| Toxicity | topic | 2 | |
| Vaccine Injury | condition | 1 | |
| Vasorelaxant | property | 3 | Lowers blood pressure |
| Veterinary Use | topic | 1 | Veterinary uses of cannabinoids (cats and dogs) |
| Weight Loss | topic | 9 |
See also: obesity |
| Tourette Syndrome | condition | 7 |
Verdict: Positive with Medium evidence level Tics due to Tourette Syndrome respond to cannabis preparations |
| Bone Health | topic | 1 |
| Compond | Class (Boil Pt) | # of Papers | Description |
|---|---|---|---|
| cannabinoids | 53 | Catch-all for cannabinoid subjects and studies | |
| cannabis | 173 | Catch-all for medical cannabis topics and studies | |
| Cannabichromene (CBC) | cannabinoid (220℃) | 7 | Cannabichromene (CBC), also called cannabichrome, cannanbichromene, pentylcannabichromene or cannabinochromene, is one of the 120 cannabinoids found in the Cannabis plant. [Link] |
| Cannabidiol (CBD) | cannabinoid (180℃) | 115 | The second most common phytocannibanoid [Link] |
| Cannabidivarin (CBDV) | cannabinoid (165℃) | 6 | Cannabidivarin (CBDV) is a non-psychoactive cannabinoid found in Cannabis. It is a homolog of cannabidiol (CBD), with the side-chain shortened by two methylene bridges (CH2 units) [Link] |
| Cannabigerol (CBG) | cannabinoid (52℃) | 11 | Cannabigerol is the non-acidic form of cannabigerolic acid, the parent molecule from which other cannabinoids are synthesized. Cannabigerol is a minor constituent of cannabis [Link] |
| Cannabinol (CBN) | cannabinoid (185℃) | 7 | Cannabinol is a slightly psycoative, more sedative oxidation by-product of THC [Link] |
| Tetrahydrocannabinol (THC) | cannabinoid (157℃) | 65 | The principal psychoactive constituent of cannabis [Link] |
| Tetrahydrocannabivarin (THCV) | cannabinoid (220℃) | 6 | Cannibanoid with more intense, shorter-lasting effects then THC [Link] |
| Abnormal Cannabidiol (Abn-CBD) | cannabinoid (synthetic) | 1 | Abnormal cannabidiol (Abn-CBD) is a synthetic regioisomer of cannabidiol, which unlike most other cannabinoids produces vasodilator effects, lowers blood pressure, and induces cell migration, cell proliferation and mitogen-activated protein kinase activation in microglia, but without producing any psychoactive effects. [Link] |
| AM251 | cannabinoid (synthetic) | 3 | AM-251 is an inverse agonist at the CB1 cannabinoid receptor. AM-251 is structurally very close to SR141716A (rimonabant); both are biarylpyrazole cannabinoid receptor antagonists [Link] |
| AM6545 | cannabinoid (synthetic) | 4 | AM-6545 is a drug which acts as a peripherally selective silent antagonist for the CB1 receptor, and was developed for the treatment of obesity. [Link] |
| CR701 | cannabinoid (synthetic) | 0 | Caras most advanced CB compound, CR701, is in preclinical development. [Link] |
| Dronabinol | cannabinoid (synthetic) | 5 | Dronabinol, sold as trade names Marinol and Syndros, is an appetite stimulant, antiemetic, and sleep apnea reliever. [Link] |
| H2CBD | cannabinoid (synthetic) | 1 | 8,9-dihydrocannibidiol (H2CBD) is a fully synthetic analogue of CBD that is prepared from inexpensive, non-cannabis derived precursors. |
| HU-210 | cannabinoid (synthetic) | 2 | HU-210 is a synthetic cannabinoid that was first synthesized in 1988 from (1R,5S)-myrtenol by a group led by Raphael Mechoulam at the Hebrew University. HU-210 is 100 to 800 times more potent than natural THC from cannabis and has an extended duration of action. [Link] |
| HU-308 | cannabinoid (synthetic) | 1 | HU-308 is a drug that acts as a cannabinoid agonist. It is highly selective for the CB2 receptor subtype, with a selectivity of over 5000x for CB2 vs CB1 [Link] |
| HU-331 | cannabinoid (synthetic) | 2 | HU-331 is a quinone anticarcinogenic drug synthesized from cannabidiol, a cannabinoid in the Cannabis sativa plant. [Link] |
| JWH-015 | cannabinoid (synthetic) | 5 | JWH-015 is a chemical from the naphthoylindole family that acts as a subtype-selective cannabinoid agonist. [Link] |
| JWH-018 | cannabinoid (synthetic) | 1 | JWH-018 (or AM-678) is an analgesic chemical from the naphthoylindole family that acts as a full agonist at both the CB1 and CB2 cannabinoid receptors, with some selectivity for CB2. It produces effects in animals similar to those of tetrahydrocannabinol (THC). [Link] |
| JWH-133 | cannabinoid (synthetic) | 5 | JWH-133 is a potent selective CB2 receptor agonist with a Ki of 3.4nM and selectivity of around 200x for CB2 over CB1 receptors. [Link] |
| JZL184 | cannabinoid (synthetic) | 1 | JZL184 is an irreversible inhibitor for monoacylglycerol lipase (MAGL), the primary enzyme responsible for degrading the endocannabinoid 2-arachidonoylglycerol (2-AG). [Link] |
| Nabilone | cannabinoid (synthetic) | 9 | Nabilone, sold under the brand name Cesamet among others, is a synthetic cannabinoid with therapeutic use as an antiemetic and as an adjunct analgesic for neuropathic pain. [Link] |
| O-1602 | cannabinoid (synthetic) | 2 | O-1602 does not bind to the classical cannabinoid receptors CB1 or CB2 with any significant affinity, but instead is an agonist at several other receptors which appear to be related to the cannabinoid receptors, particularly GPR18 and GPR55. [Link] |
| O-1966 | cannabinoid (synthetic) | 1 | |
| PF3845 | cannabinoid (synthetic) | 1 | PF-3845 is a selective inhibitor of fatty acid amide hydrolase, which results in increased levels of anandamide and thus cannabinoid receptor-based effects. [Link] |
| Rimonabant | cannabinoid (synthetic) | 10 | Rimonabant (also known as SR141716; trade names Acomplia, Zimulti)[3] is an anorectic antiobesity drug that was first approved in Europe in 2006 but was withdrawn worldwide in 2008 due to serious psychiatric side effects; it was never approved in the United States. [Link] |
| WIN-55,212-2 (WIN55) | cannabinoid (synthetic) | 11 | WIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure [Link] |
| WWL70 | cannabinoid (synthetic) | 1 | WWL70 is a selective inhibitor of alpha-/beta--hydrolase domain-containing 6 (ABHD6), a serine hydrolase that acts as an alternative hydrolase of the endocannabinoid 2-arachidonoylglycerol (2-AG). [Link] |
| Zygel (ZYN002) | cannabinoid (synthetic) | 1 | CONNECT-FX is a clinical trial evaluating ZYN002, an experimental transdermally delivered CBD gel, as a treatment for some of the common and debilitating behaviors in patients with FXS [Link] |
| Nabiximols (Sativex) | concentrate | 7 | Nabiximols is a specific extract of Cannabis (1:1) that was approved as a botanical drug in the United Kingdom in 2010 as a mouth spray to alleviate neuropathic pain, spasticity, overactive bladder, and other symptoms of multiple sclerosis; it was developed by the UK company GW Pharmaceuticals. [Link] |
| Epidiolex | concentrate | 3 | High-CBD cannabis extract aproved for the treament of seizures [Link] |
| 2-Arachidonoylglycerol (2AG) | endocannabinoid | 2 | 2-Arachidonoylglycerol (2-AG) is an endocannabinoid, an endogenous agonist of the CB1 receptor and the primary endogenous ligand for the CB2 receptor. [Link] |
| Anandamide (ANA) | endocannabinoid | 5 | Anandamide (also known as N-arachidonoylethanolamine or AEA), is a fatty acid neurotransmitter derived from the non-oxidative metabolism of eicosatetraenoic acid (arachidonic acid), an essential o-6 polyunsaturated fatty acid. [Link] |
| Cannflavin | flavonoid | 3 | Cannflavins are a group of chemical compounds found in Cannabis sativa. Chemically, they are prenylflavonoids and are unrelated to THC and other cannabinoids. [Link] |
| Satipharm CBD Gelpell (PTL101) | isolate | 1 | The PTL101 drug beads utilise a proprietary formulation developed through Satipharms Gelpell-CBD(TM) product technology, which contain organically derived, highly purified CBD [Link] |
| AM404 | metabolite | 1 | AM404, also known as N-arachidonoylaminophenol,[1] is an active metabolite of paracetamol (acetaminophen), responsible for all or part of its analgesic action[2] and anticonvulsant effects. [Link] |
| 11-Nor-9-carboxy-THC (THC-COOH) | metabolite | 2 | 11-Nor-9-carboxy-delta-9-tetrahydrocannabinol (11-COOH-THC or THC-COOH), often referred to as 11-nor-9-carboxy-THC or THC-11-oic acid, is the main secondary metabolite of tetrahydrocannabinol (THC), which is formed in the body after cannabis is consumed. [Link] |
| 11-Hydroxy-THC (THC-OH) | metabolite | 1 | 11-Hydroxy-delta-9-tetrahydrocannabinol (11-OH-THC), usually referred to as 11-hydroxy-THC, is the main active metabolite of tetrahydrocannabinol (THC), which is formed in the body after decarboxylated cannabis is consumed [Link] |
| Rho-Cymene (Cymene) | monoterpene (177℃) | 7 | Rho-Cymene has a musty scent and is found naturally in thyme, cumin and other spices.
[Link]
Flavors: Spicy Also in: coriander, eucalyptus, marjoram |
| Eucalyptol | monoterpene (177℃) | 1 | Eucalyptol comprises up to 90% of the essential oil of some species of the generic product eucalyptus oil,[1] hence the common name of the compound.
[Link]
Flavors: Mint, Spicy Also in: Wormwood, Rosemary, Sage |
| Geraniol | monoterpene (230℃) | 7 | An acyclic monoterpene alcohol with a sweet rose-like aroma.
[Link]
Flavors: Flower Also in: roses, lemon grass, blueberries, lemons peels, and carrots, |
| D-Limonene (Limonene) | monoterpene (176℃) | 21 | Limonene is found in the peels and oils of many citrus fruits, including lemon, orange, mandarin, lime, and grapefruit.
[Link]
Flavors: Citrus Also in: Citrus Rinds, Juniper, Peppermint |
| Linalool | monoterpene (198℃) | 25 | Linalool is a monoterpene compound, commonly found as major component of essential oils of several aromatic species, many of which are used traditionally as sedatives.
[Link]
Flavors: Floral Also in: Lavender, Citrus, Laurel, Birch, Rosewood |
| Beta-Myrcene (Myrcene) | monoterpene (167℃) | 11 | Most commonly found terpene in cannabis.
[Link]
Flavors: Musky Also in: Mango, Thyme, Citrus, Lemongrass, Bay Leaves |
| Ocimene | monoterpene (55-65℃) | 4 | Ocimene is a cannabis terpene carrying a sweet, herbaceous, and earthy aroma with hints of citrus.
[Link]
Flavors: Fruity Also in: mint, parsley, pepper, basil, mangoes, orchids |
| Alpha-Pinene (Pinene) | monoterpene (155℃) | 15 | Alpha-pinene has a woody and earthy aroma, with clear cedarwood and pine tones
[Link]
Flavors: Pine, Herb Also in: Pine Needles, Sage, Eucalyptus, Conifers |
| Terpineol | monoterpene (219℃) | 3 | Terpineol has a pleasant odor similar to lilac and is a common ingredient in perfumes, cosmetics, and flavors.
[Link]
Flavors: Sweet, Lilac Also in: Cajuput, Pine, Petitgrain |
| Alpha-Bisabolol (Bisabolol) | sesquiterpene (153℃) | 9 | Bisabolol is a cannabis terpene boasting a delicately sweet and floral aroma with hints of citrus and spice.
[Link]
Flavors: Sweet Also in: chamomile flower, candeia tree |
| Beta-Caryophyllene (Caryophyllene) | sesquiterpene (130℃) | 21 | The terpene that's also a cannibanoid, capable of interacting with CB2 endoctrine receptors.
[Link]
Flavors: Woody Also in: Peper, Cloves, Hops, Basil, Oregano |
| Guaiol | sesquiterpene (92℃) | 4 | Unlike most cannabis terpenes, guaiol is classified as a sesquiterpenoid alcohol.
[Link]
Flavors: Piney Also in: Guaiacum tree |
| Alpha-Humulene (Humulene) | sesquiterpene (106℃) | 7 | Humulene is an isomer of caryophyllene that's been shown to interact directly with the endocrtine system
[Link]
Flavors: Woody Also in: Hops, Coreander |
| Borneol | terpene (213℃) | 9 | Borneol is a bicyclic organic compound and a terpene derivative.
[Link]
Flavors: Minty Also in: Camphor, rosemary, mint plants |
| Eugenol | terpene (254℃) | 2 | Eugenol is an allyl chain-substituted guaiacol, a member of the allylbenzene class of chemical compounds.
[Link]
Also in: Cloves, Nutmeg, Dill, Ginger |
| Trans-Nerolidol (Nerolidol) | terpene (122℃) | 7 | Nerolidol is a terpene that is also known as peruviol, and has two isomers and is a sesquiterpene which means it is more stable than other terpenes.
[Link]
Flavors: Woody Also in: Ginger, Jasmne, Lavender |
| Alpha/Beta-Phellandrene (Phellandrene) | terpene (171℃) | 4 | Phellandrene is the name for a pair of organic compounds that have a similar molecular structure and similar chemical properties.
[Link]
Flavors: Mint, Citrus Also in: Allspice, Eucalyptus |
| Gamma-Terpinene (Terpinene) | monoterpene (174℃) | 3 | The terpinenes are a group of isomeric hydrocarbons that are classified as monoterpenes.
[Link]
Flavors: Spicy, Cloves Also in: Cumin, Mint |
| Delta-Terpinene (Terpinolene) | monoterpene (186℃) | 6 | Terpinolene is the terpene partly responsible for the woody, piney smell cannabis can often have.
[Link]
Flavors: Woody Also in: Tea Tree, Conifers, apple, sage, cumin, rosemary, lilac |
| SEDDS-CBD | concentrate | 1 | A self-microemulsifying drug delivery system (SMEDDS) is a drug delivery system that uses a microemulsion achieved by chemical rather than mechanical means. [Link] |