Caryophyllene
The terpene that's also a cannibanoid, capable of interacting with CB2 endoctrine receptors.
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Uses Title Date
pain
Involvement of peripheral cannabinoid and opioid receptors in Beta-caryophyllene-induced antinociception May 2013
depression
anxiety
Beta-Caryophyllene, a CB2 receptor agonist produces multiple behavioral changes relevant to anxiety and depression in mice Aug 2014
anti-inflamatory (gastric)
Gastric cytoprotection of the non-steroidal anti-inflammatory sesquiterpene, beta-caryophyllene. Oct 1996
anti-inflamatory
pain
The cannabinoid CB2 receptor-selective phytocannabinoid beta-caryophyllene exerts analgesic effects in mouse models of inflammatory and neuropathic pain. Apr 2014
cancer
Potentiating effect of beta-caryophyllene on anticancer activity of alpha-humulene, isocaryophyllene and paclitaxel. Dec 2007
anti-inflamatory
Beta-Caryophyllene inhibits dextran sulfate sodium-induced colitis in mice through CB2 receptor activation and PPAR? pathway Mar 2011
osteoartritis
Evaluation of the anti-inflammatory, anti-catabolic and pro-anabolic effects of E-caryophyllene, myrcene and limonene in a cell model of osteoarthritis Mar 2015
diabetes
Beta-Caryophyllene, a natural sesquiterpene, modulates carbohydrate metabolism in streptozotocin-induced diabetic rats. Oct 2014
anti-fibrosis (liver)
The anti-oxidant effect of Beta-caryophyllene protects rat liver from carbon tetrachloride-induced fibrosis by inhibiting hepatic stellate cell activation Feb 2013
anti-oxidant
cancer
The Anticancer, anti-oxidant and Antimicrobial Properties of the Sesquiterpene Beta-Caryophyllene from the Essential Oil of Aquilaria crassna Jun 2015
pain
Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis cohort May 2018
anxiety
Cannabis Essential Oil: A Preliminary Study for the Evaluation of the Brain Effects. Jan 2018
anti-inflamatory
Anti-inflammatory and anti-edematogenic action of the Croton campestris A. St.-Hil (Euphorbiaceae) essential oil and the compound ?-caryophyllene in in vivo models. Mar 2018
anti-microbial
Caryophyllene-rich rhizome oil of Zingiber nimmonii from South India: Chemical characterization and antimicrobial activity. Feb 2006
anti-inflamatory
Beta-caryophyllene is a dietary cannabinoid Jul 2008
diabetes
pain
depression
Beta-Caryophyllene, a Natural Sesquiterpene, Attenuates Neuropathic Pain and Depressive-Like Behavior in Experimental Diabetic Mice Mar 2019