| Compounds | Topics | Title | Date |
|---|---|---|---|
| Guaiol | laxative via review | Pubchem - Guaiol | Jan 2019 |
| Used by herbalists as a laxative; diuretic. | |||
| Guaiol | cancer,lung cancer in mice via experiment | (-)-Guaiol regulates RAD51 stability via autophagy to induce cell apoptosis in non-small cell lung cancer | Sept 2016 |
|
Action Pathway: RAD51 The following mechanism studies show that (-)-Guaiol is involved in cell autophagy to regulate the expression of RAD51, leading to double-strand breaks triggered cell apoptosis. | |||
| Guaiol | anti-bacterial,anti-oxidant | The essential oil from the fruits of the Brazilian spice Xylopia sericea A. St.-Hil. presents expressive in-vitro anti-bacterial and anti-oxidant activity. | Mar 2017 |
|
Ingestion Method: Xylopia sericea fruits (OXS) OXS presented a significant antioxidant activity and also a high bacteriostatic effect against Staphylococcus aureus, Enterobacter cloacae, Bacillus cereus and Klebsiella pneumoniae. | |||
| Guaiol,Caryophyllene | cancer,lung cancer in vitro via experiment | Bulnesia sarmientoi Supercritical Fluid Extract Exhibits Necroptotic Effects and Anti-Metastatic Activity on Lung Cancer Cells. | Dec 2018 |
| alpha--Guaiene, (-)-guaiol and beta--caryophyllene are responsible for most of the cytotoxic activity of BSE against these two cancer cell lines. Since BSE possesses significant cytotoxicity and anti-metastatic activity on A549 and H661 cells, it may serve as a potential target for the treatment of lung cancer. | |||