Cannabis and HU-308
Browse the latest research linking medical marijuana / medicinal cannabis and HU-308 (a cannabinoid (synthetic))

Action: CB2 agonist
HU-308 is a drug that acts as a cannabinoid agonist. It is highly selective for the CB2 receptor subtype, with a selectivity of over 5000x for CB2 vs CB1 [Wikipedia]
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Compounds Topics Title Date
HU-308 anti-inflamatory,arthritis in vitro Expression of cannabinoid receptor 2 and its inhibitory effects on synovial fibroblasts in rheumatoid arthritis May 2014
Action Pathway: CB2
In RA-FLS, proinflammatory mediators up-regulate the expression of CB2R, which negatively regulates the production of proinflammatory cytokines and MMPs. These data suggest that CB2R may be a potential therapeutic target of RA.
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