|Borneol||anti-fibrosis in mice via model||Influence of borneol on primary mice oral fibroblasts: a penetration enhancer may be used in oral submucous fibrosis.||Mar 2009|
Ingestion Method: 18.75 to 300 microg/ml|
This study indicates that borneol has anti-fibrosis activity and the mechanism may partly be relevant to its inhibiting effects on fibroblasts mitosis, collagen and TIMP-1 production. It can be safely used as a penetration enhancer for our formula to treat OSF.
|Caryophyllene||anti-fibrosis,anti-oxidant in vitro||The anti-oxidant effect of Beta-caryophyllene protects rat liver from carbon tetrachloride-induced fibrosis by inhibiting hepatic stellate cell activation||Feb 2013|
Ingestion Method: 1 and 10 um|
CAR, a sesquiterpene present in numerous plants and foods, is as a natural antioxidant that reduces carbon tetrachloride-mediated liver fibrosis and inhibits hepatic cell activation.