Cannabis and ibd
Browse the latest research linking medical marijuana / medicinal cannabis and ibd.

See also: crohns 
Click on a study title below to open a new tab with full article, or click on a compound to see it's full list of research.
Compounds Topics Title Date
Caryophyllene anti-inflamatory,ibd in mice via experiment Beta-Caryophyllene inhibits dextran sulfate sodium-induced colitis in mice through CB2 receptor activation and PPARg pathway Mar 2011
Ingestion Method: 12.5, 25, or 50 mg/kg, p.o.
Action Pathway: CB2,PPARg
These results demonstrate that the anti-inflammatory effect of BCP involves CB2 and the PPARg pathway and suggest BCP as a possible therapy for the treatment of inflammatory bowel disease.
CBD ibd,anti-inflamatory in mice An Orally Active Cannabis Extract with High Content in Cannabidiol attenuates Chemically-induced Intestinal Inflammation and Hypermotility in the Mouse Oct 2016
In conclusion, CBD BDS, given after the inflammatory insult, attenuates injury and motility in intestinal models of inflammation. These findings sustain the rationale of combining CBD with other minor Cannabis constituents and support the clinical development of CBD BDS for IBD treatment.
cannabinoids ibd,colon cancer in vitro Members of the endocannabinoid system are distinctly regulated in inflammatory bowel disease and colorectal cancer Feb 2019
There is still a wide gap between preclinical evidence and the role of the ECS in human GI diseases. So far, little evidence exists whether cannabinoids are beneficial in human IBD and CRC, as large clinical trials are still missing.
cannabis ibd,crohns in humans via review Cannabis, Cannabinoids, and the Endocannabinoid System--Is there Therapeutic Potential for Inflammatory Bowel Disease? Mar 2019
Positive  Research into the distribution and function of the endocannabinoid system in IBD and models of intestinal inflammation is increasing. There is accumulating evidence that enhancing signalling through cannabinoid receptors 1 and 2 has anti-inflammatory potential in the intestine in vivo
CBD crohns,ibd in humans via placebo trial (n=20) Low-Dose Cannabidiol Is Safe but Not Effective in the Treatment for Crohn's Disease, a Randomized Controlled Trial. Jun 2017
Ingestion Method: 10mg
Negative  In this study of moderately active Crohn's disease, CBD was safe but had no beneficial effects. This could be due to lack of effect of CBD on Crohn's disease, but could also be due to the small dose of CBD, the small number of patients in the study, or the lack of the necessary synergism with other cannabinoids
cannabis ibd in humans via survey (n=99) Marijuana Use by Adolescents and Young Adults with Inflammatory Bowel Disease Jun 2017
Positive  Marijuana use by adolescents and young adults with IBD is common and perceived as beneficial.
cannabinoids ibd in rats Cannabinoid-induced relief of hypermotility in a rat model of the irritable bowel syndrome. May 2019
Cannabinoid-2 receptor agonists may be useful in treating intestinal motility disorders.
cannabis ibd in humans via study (n=6002) In-hospital outcomes of inflammatory bowel disease in cannabis users: a nationwide propensity-matched analysis in the United States. Jun 2019
We found a lower frequency of colorectal cancer, parenteral nutrition, anemia but a higher occurrences of active fistulizing disease or intraabdominal abscess formation, lower GI hemorrhage and hypovolemia in the CD cohort with cannabis usage.