Compounds | Topics | Title | Date |
---|---|---|---|
Limonene | anti-oxidant,anti-inflamatory,intenstine in rats | D-limonene exhibits anti-inflammatory and anti-oxidant properties in an ulcerative colitis rat model via regulation of iNOS, COX-2, PGE2 and ERK signaling pathways. | Apr 2017 |
Action Pathway: iNOS, COX-2, PGE2, TGF-beta- In conclusion, D-limonene reduced MMP-2 and -9 mRNA expression levels via regulation of the iNOS, COX-2, PGE2, TGF-beta- and ERK1/2 signaling pathways in a UC rat model, indicating its potential antioxidant and anti-inflammatory properties. |