Cannabis and neuroprotective
Browse the latest research linking medical marijuana / medicinal cannabis and neuroprotective.

See also: parkinsons 
Click on a study title below to open a new tab with full article, or click on a compound to see it's full list of research.
Compounds Topics Title Date
CBG hungtingtons disease,neuroprotective in mice via experiment Neuroprotective Properties of Cannabigerol in Huntingtons Disease: Studies in R6/2 Mice and 3-Nitropropionate-lesioned Mice Jan 2015
CBG was extremely active as neuroprotectant in mice intoxicated with 3-nitropropionate (3NP), improving motor deficits and preserving striatal neurons against 3NP toxicity.
CBD epilepsy,anti-inflamatory,neuroprotective via review Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders May 2014
The antiepileptic mechanisms of CBD are not known, but may include effects on the equilibrative nucleoside transporter; the orphan G-protein-coupled receptor GPR55; the transient receptor potential of melastatin type 8 channel; the 5-HT1a receptor; the alpha-3 and alpha-1 glycine receptors; and the transient receptor potential of ankyrin type 1 channel. CBD has neuroprotective and anti-inflammatory effects.
Nerolidol anti-inflamatory,parkinsons,neuroprotective in mice Neuroprotective effect of nerolidol against neuroinflammation and oxidative stress induced by rotenone Aug 2016
Our findings are the first to show that the neuroprotective effect of nerolidol is mediated through its anti-oxidant and anti-inflammatory activities, which strongly supports its therapeutic potential for the treatment of PD.
THC neuroprotective in mice via experiment Pre- and post-conditioning treatment with an ultra-low dose of delta-9-tetrahydrocannabinol (THC) protects against pentylenetetrazole (PTZ)-induced cognitive damage. Jun 2011
Ingestion Method: 0.002 mg/kg
We found that a single administration of THC either before or after PTZ abolished the PTZ-induced long-lasting cognitive deficits.
CBG neuroprotective,hungtingtons disease in mice Neuroprotective properties of cannabigerol in Huntington's disease: studies in R6/2 mice and 3-nitropropionate-lesioned mice. Jan 2015
CBG was extremely active as neuroprotectant in mice intoxicated with 3-nitropropionate (3NP), improving motor deficits and preserving striatal neurons against 3NP toxicity. In addition, CBG attenuated the reactive microgliosis and the upregulation of proinflammatory markers induced by 3NP, and improved the levels of antioxidant defenses that were also significantly reduced by 3NP.
THC neuroprotective in mice via experiment A chronic low dose of delta-9-tetrahydrocannabinol (THC) restores cognitive function in old mice. Jun 2017
THC treatment restored hippocampal gene transcription patterns such that the expression profiles of THC-treated mice aged 12 months closely resembled those of THC-free animals aged 2 months.
CBD alzheimers,neuroprotective in vitro via experiment Cannabidiol Reverses Deficits in Hippocampal LTP in a Model of Alzheimer's Disease. Mar 2019
Action Pathway: PPARg
However in the presence of the PPARg antagonist GW9662 the neuroprotective effect of CBD was prevented. Our data suggests that this major component of Cannabis sativa, which lacks psychoactivity may have therapeutic potential for the treatment of AD.
CBD,CBDV neuroprotective in vitro Low doses of widely consumed cannabinoids (cannabidiol and cannabidivarin) cause DNA damage and chromosomal aberrations in human-derived cells. Jan 2019
Negative  Both compounds induced DNA damage in single cell gel electrophoresis (SCGE) experiments in a human liver cell line (HepG2) and in buccal-derived cells (TR146) at low levels (>= 0.2 uM).