| CBD |
addiction,nicotine
in humans via placebo trial (n=24) |
Cannabidiol reduces cigarette consumption in tobacco smokers: preliminary findings. |
Sept 2013 |
|
Positive
Over the treatment week, placebo treated smokers showed no differences in number of cigarettes smoked. In contrast, those treated with CBD significantly reduced the number of cigarettes smoked by ~40% during treatment. Results also indicated some maintenance of this effect at follow-up.
|
| THCV |
addiction,nicotine
in rats via experiment |
Tetrahydrocannabivarin has potent anti-nicotine effects in multiple rodent models of nicotine dependence. |
Aug 2019 |
|
We conclude that delta-8 -THCV may have therapeutic potential for the treatment of nicotine dependence. We also suggest that tetrahydrocannabivarins should be tested for possible anti-addiction efficacy in a broader range of preclinical animal models, against other addictive drugs, and eventually in humans.
|