| cannabis |
pregnancy
in humans via study (n=661617) |
Association Between Self-reported Prenatal Cannabis Use and Maternal, Perinatal, and Neonatal Outcomes |
Jun 2019 |
|
Negative
Reported cannabis use in pregnancy was associated with significant increases in the rate of preterm birth following adjustment for confounding.
|
| cannabis |
pregnancy
via review |
Is Increasing Frequency of Marijuana Use Among Women of Reproductive Age a Cause for Alarm? |
Jul 2019 |
|
Negative
In short, the observed increase is likely to be representative of a true increase in marijuana use and frequency of use among reproductive-aged women over the past decade. There are data indicating that adverse pregnancy outcomes such as low birth weight, preterm birth, and abnormal neurologic development may be affected by frequency of use. With this knowledge, the findings in the study by Young-Wolff and colleagues are cause for alarm.
|
| cannabis |
pregnancy
in humans via study (n=1206) |
Marijuana use in young mothers and adverse pregnancy outcomes: a retrospective cohort study |
Jul 2019 |
|
Negative
In a population of young women with nearly universal biologic sampling, marijuana exposure was associated with adverse pregnancy outcomes.
|
| cannabis |
pregnancy
in humans via survey (n=26654) |
SOCIOECONOMIC STATUS AND ADVERSE BIRTH OUTCOMES: A POPULATION-BASED CANADIAN SAMPLE. |
Jan 2018 |
|
Negative
2.72x odds of low birth weight with maternal marijuana use.
|
| cannabis |
pregnancy
in humans via review |
Cannabis Use in Pregnancy in British Columbia and Selected Birth Outcomes |
Feb 2019 |
|
Negative
Using cannabis in pregnancy was associated with a 47% increased risk of SGA (adjusted OR 1.47; 95% CI 1.33-1.61), a 27% increased risk of spontaneous preterm birth (adjusted OR 1.27; 95% CI 1.14-1.42), and a 184% increased risk of intrapartum stillbirth (adjusted HR [aHR] 2.84; 95% CI 1.18-6.82)
|
| cannabis,THC |
pregnancy
in vitro |
delta-9-Tetrahydrocannabinol leads to endoplasmic reticulum stress and mitochondrial dysfunction in human BeWo trophoblasts. |
May 2019 |
|
Negative
Collectively, these findings indicate that delta-9-THC can directly augment ER stress resulting in aberrant placental gene expression and impaired mitochondrial function.
|
| cannabis |
pregnancy
in humans via survey (n=661617) |
Association Between Self-reported Prenatal Cannabis Use and Maternal, Perinatal, and Neonatal Outcomes. |
Jun 2019 |
|
Negative
Among pregnant women in Ontario, Canada, reported cannabis use was significantly associated with an increased risk of preterm birth. Findings may be limited by residual confounding.
|
| cannabis |
pregnancy
via review |
Marijuana Use in Pregnancy: A Review. |
Jul 2019 |
|
Negative
Available studies on marijuana exposure in pregnancy were reviewed and support some degree of developmental disruption, including an increased risk of fetal growth restriction and adverse neurodevelopmental consequences. However, much of the existing prenatal marijuana research was performed in the 1980s, when quantities of THC were lower and the frequency of use was less.
|
| cannabis |
pregnancy
in humans via study |
Interaction of maternal choline levels and prenatal Marijuana's effects on the offspring |
Jul 2019 |
|
Prenatal marijuana use adversely affects fetal brain development and subsequent behavioral self-regulation, a precursor to later, more serious problems in childhood. Stopping marijuana use before 10 weeks gestational age prevented these effects.
|