|CBD||anxiety,stress in mice via experiment||The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system||Jul 2013|
Ingestion Method: 30 mg/kg i.p.|
Action Pathway: CB1
These findings support that the anxiolytic effect of chronic CBD administration in stressed mice depends on its proneurogenic action in the adult hippocampus by facilitating endocannabinoid-mediated signalling.
|Limonene||stress in mice||Anti-stress effects of d-limonene and its metabolite perillyl alcohol||Apr 2014|
|In addition to its anti-inflammatory effects, a beneficial role as an anti-stress substance could thus be claimed for d-limonene used as a dietary supplement.|
|cannabinoids||anxiety,stress in rats via review||Endocannabinoids and striatal function: implications for addiction-related behaviours.||Feb 2015|
|In this article we integrate and discuss recent findings in rodents showing selective pharmacological modulation of impulsivity and anxiety by cannabinoid agents. We highlight the potential of selective inhibitors of endocannabinoid metabolism, directed at fatty acid amide hydrolase and monoacylglycerol lipase, to reduce anxiety and stress responses, and discuss novel mechanisms underlying the modulation of the endocannabinoid system, including the attenuation of impulsivity, anxiety, and drug reward by selective CB2 receptor agonists.|