|CBD||vasorelaxant,anti-inflamatory in vitro||Cannabidiol causes endothelium-dependent vasorelaxation of human mesenteric arteries via CB1 activation||Sept 2015|
Action Pathway: CB1,TRP|
This study shows, for the first time, that CBD causes vasorelaxation of human mesenteric arteries via activation of CB1 and TRP channels, and is endothelium- and nitric oxide-dependent.
|Limonene||diabetes,vasorelaxant in rats||Dietary d-limonene alleviates insulin resistance and oxidative stress-induced liver injury in high-fat diet and L-NAME-treated rats.||Feb 2012|
Ingestion Method: oral|
Dietary supplementation with d-limonene reversed the HFD and L-NAME-induced changes and restored pathological alteration of liver and pancreas.
|Linalool||vasorelaxant in rats via experiment||Cardiovascular effects induced by linalool in normotensive and hypertensive rats.||May 2013|
Ingestion Method: 200 mg/kg BW; oral (v.o.)|
In conclusion, these results demonstrate that linalool reduces blood pressure probably due to a direct effect on the vascular smooth muscle leading to vasodilation.