Cannabis and glioma
Browse the latest research linking medical marijuana / medicinal cannabis and glioma.

See also: cancer 
Click on a study title below to open a new tab with full article, or click on a compound to see it's full list of research.
Compounds Topics Title Date
CBD cancer,glioma in vitro via experiment Cannabidiol inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism Apr 2005
These results reinforce the evidence of antitumoral properties of CBD, demonstrating its ability to limit tumor invasion, although the mechanism of its pharmacological effects remains to be clarified.
CBD,THC cancer,glioma in vitro Cannabidiol enhances the inhibitory effects of delta-9-tetrahydrocannabinol on human glioblastoma cell proliferation and survival Jan 2010
Our results suggest that the addition of CBD to delta-9-THC may improve the overall effectiveness of delta-9-THC in the treatment of glioblastoma in cancer patients.
JWH-133 cancer,glioma in mice via experiment Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor. Aug 2001
Ingestion Method: 50 microg/day
Action Pathway: CB2
Experiments carried out with C6 glioma cells in culture evidenced the internalization of the CB(2) but not the CB(1) receptor upon JWH-133 challenge and showed that selective activation of the CB(2) receptor signaled apoptosis via enhanced ceramide synthesis de novo. These results support a therapeutic approach for the treatment of malignant gliomas devoid of psychotropic side effects.
CBD cancer,glioma in mice via experiment Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines. Mar 2004
In conclusion, the nonpsychoactive CBD was able to produce a significant antitumor activity both in vitro and in vivo, thus suggesting a possible application of CBD as an antineoplastic agent.
cannabinoids cancer,glioma in vitro Cannabinoid receptors in human astroglial tumors. Aug 2006
We conclude that cannabinoid therapy of human gliomas targets not only receptors on tumor, but also on other cell types. Therefore, complex and potential side-effects should be considered carefully.
cannabinoids cancer,glioma in vitro Predominant CB2 receptor expression in endothelial cells of glioblastoma in humans. Jun 2009
Action Pathway: CB2
In glioblastoma endothelial cells, CB1 and CB2 receptors were present in about 38% and 54% of the cells respectively. In comparison to CB1, an elevated CB2 receptor expression was identified in glioblastoma.
WIN55 cancer,glioma in vitro Opposite changes in cannabinoid CB1 and CB2 receptor expression in human gliomas. May 2010
The present results demonstrate opposite changes in CB(1) and CB(2) receptor protein expression in human gliomas. These changes may be of interest for further research about the therapeutic effects of cannabinoids in glial tumors.
cannabinoids cancer,glioma via review Systematic review of the literature on clinical and experimental trials on the antitumor effects of cannabinoids in gliomas. Jan 2014
Positive  In all experimental studies included, cannabinoids exerted antitumoral activity in vitro and/or antitumoral evidence in vivo in several models of tumor cells and tumors.